Derailing individualized ovarian stimulation

No abstract available

Strain Analysis of Initial Stage Sintering of 316L SS Three Dimensionally Printed (3DP TM) Components

Mechanical Engineerin

Researching a segmented market:reflections on telephone interviewing

Purpose The purpose of this paper was to review the effectiveness of telephone interviewing for capturing data and to consider in particular the challenges faced by telephone interviewers when capturing information about market segments. Design/methodology/approach The platform for this methodological critique was a market segment analysis commissioned by Sport Wales which involved a series of 85 telephone interviews completed during 2010. Two focus groups involving the six interviewers involved in the study were convened to reflect on the researchers’ experiences and the implications for business and management research. Findings There are three principal sets of findings. First, although telephone interviewing is generally a cost-effective data collection method, it is important to consider both the actual costs (i.e. time spent planning and conducting interviews) as well as the opportunity costs (i.e. missed appointments, “chasing participants”). Second, researchers need to be sensitised to and sensitive to the demographic characteristics of telephone interviewees (insofar as these are knowable) because responses are influenced by them. Third, the anonymity of telephone interviews may be more conducive for discussing sensitive issues than face-to-face interactions. Originality/value The present study adds to this modest body of literature on the implementation of telephone interviewing as a research technique of business and management. It provides valuable methodological background detail about the intricate, personal experiences of researchers undertaking this method “at a distance” and without visual cues, and makes explicit the challenges of telephone interviewing for the purposes of data capture

The Full Re-Ionization of Helium

Observations of resolved HeII Lyman alpha absorption in spectra of two QSO's suggest that the epoch of helium ionization occurred at z~3. Proximity zones in the spectra of the quasars (z=3.18, 3.285) at 304 A resemble Stromgren spheres, suggesting that the intergalactic medium is only singly ionized in helium. We present models of the proximity effect which include the full physics of the ionization, heating and cooling and an accurately simulated inhomogeneous gas distribution. In these models the underdense intergalactic medium is heated to at least 10,000-20,000 K after cooling to as low as a few 1000 K due to cosmological expansion, with higher temperatures achieved farther away from the quasar due to absorption-hardened ionizing spectra. The quasars turn on for a few times 10^7 years with a fairly steady flux output at 228 A comparable to the 304 A flux output directly observed with HST. The recoveries in the spectra occur naturally due to voids in the IGM and may provide a fairly model-independent probe of the baryon density.Comment: 5 pages, 3 figures, to appear in the proceedings of "After the Dark Ages: When Galaxies were Young (the Universe at 2<z<5)", 9th Annual October Astrophysics Conference in Marylan

From present to future : beyond becoming a nation of readers

Includes bibliographical references (p. 13-19)The work upon which this publication was based was supported in part by the Office of Educational Research and Improvement under Cooperative Agreement No. OEG 0087-C100

Unifying metastasis--Integrating intravasation, circulation and end organ colonization

Recent technological advances that have enabled the measurement of circulating tumour cells (CTCs) in patients have spurred interest in the circulatory phase of metastasis. Techniques that do not solely rely on a blood sample allow substantial biological interrogation beyond simply counting CTCs

Investigating the Bacterial Predator Bdellovibrio’s Ability to Degrade Aspartate

Bdellovibrio bacteriovorus is a predatory Gram-negative Deltaproteobacterium that attacks and invades larger Gram-negative bacteria devouring them from within (Sockett, 2004). Enzymatic results obtained in the 1970s suggest that Bdellovibrio relies on its tricarboxylic acid (TCA) cycle and the oxidation of prey cell derived amino acids (Hespell, 1976). However, annotation of the published genome of Bdellovibrio HD100 revealed that it lacked numerous genes involved with the degradation of amino acids (Rendulic, 2004). Thus it is of great interest to determine if Bdellovibrio can degrade amino acids. If it can, new genes related to the degradation of amino acids will be discovered thanks to the unique genome of Bdellovibrio. If not, new research into why Bdellovibrio is so particular about which amino acids it degrades can be started